NR3C1

gene product
GR, GRL
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
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381 antibodies from 24 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
15 antibodies
Abnova Corporation
6 antibodies
Novus Biologicals
45 antibodies
Santa Cruz Biotechnology
1 antibody
GeneTex
9 antibodies
Acris Antibodies GmbH
17 antibodies
antibodies-online
129 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
45 antibodies
Aviva Systems Biology
16 antibodies
Boster Immunoleader Biotechnology
1 antibody
Bethyl Laboratories, Inc.
4 antibodies
Signalway Antibody LLC
2 antibodies
Creative Biomart
41 antibodies
Cell Signaling Technology, Inc
4 antibodies
Enzo Life Sciences
3 antibodies
RabMAbs
5 antibodies
Proteintech Group
1 antibody
United States Biological
21 antibodies
R&D Systems
2 antibodies
Abbiotec
1 antibody
GenWay
6 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies