NR3C1

gene product
GR, GRL
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
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466 antibodies from 27 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
15 antibodies
Abnova Corporation
6 antibodies
Novus Biologicals
45 antibodies
Santa Cruz Biotechnology
1 antibody
GeneTex
8 antibodies
Biorbyt
33 antibodies
Acris Antibodies GmbH
17 antibodies
antibodies-online
124 antibodies
Cell Signaling Technology, Inc
4 antibodies
Bethyl Laboratories, Inc.
4 antibodies
Aviva Systems Biology
16 antibodies
Abgent
6 antibodies
LifeSpan BioSciences, Inc.
86 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Bioworld Technology, Inc
4 antibodies
Signalway Antibody LLC
2 antibodies
Creative Biomart
43 antibodies
Enzo Life Sciences
3 antibodies
RabMAbs
5 antibodies
United States Biological
25 antibodies
R&D Systems
2 antibodies
RayBiotech, Inc.
2 antibodies
Abbiotec
1 antibody
GenWay
6 antibodies
Sigma-Aldrich
4 antibodies
EMD Millipore
2 antibodies