NR3C1

gene product
GR, GRL
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
More gene data

Featured antibodies

Antibodies

 

Filters

Knockdown Initiative

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated in Knockdown Initative
Eligible for validation in KDI
767 antibodies from 34 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
32 antibodies
Invitrogen Antibodies
19 antibodies
Abnova Corporation
6 antibodies
Santa Cruz Biotechnology
1 antibody
GeneTex
13 antibodies
antibodies-online
213 antibodies
Acris Antibodies GmbH
19 antibodies
Biorbyt
53 antibodies
Enzo Life Sciences
3 antibodies
Cell Signaling Technology, Inc
4 antibodies
LifeSpan BioSciences, Inc.
112 antibodies
Bethyl Laboratories, Inc.
8 antibodies
Aviva Systems Biology
17 antibodies
OriGene
27 antibodies
Abgent
10 antibodies
NovoPro Bioscience Inc.
11 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Bioworld Technology, Inc
4 antibodies
BosterBio
2 antibodies
NSJ Bioreagents
2 antibodies
Signalway Antibody LLC
2 antibodies
MyBioSource
23 antibodies
St John's Laboratory
9 antibodies
RabMAbs
5 antibodies
United States Biological
101 antibodies