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LearnFAB426A
antibody from Novus Biologicals
Targeting: TNFRSF1B
CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB426A - Provider product page
- Provider
- Novus Biologicals
- Product name
- Hamster Monoclonal TNF RII/TNFRSF1B Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse TNF RII/TNFRSF1B in ELISAs and Western blots. In sandwich immunoassays, no cross-reactivity with recombinant human (rh) TNF RII/TNFRSF1B, recombinant mouse (rm) TNF RI, rhTNF RI, rm4-1BB, or rmOPG is observed. In Western blots, approximately 25% cross-reactivity with rhDR3 and rhTNF RII is observed and no cross-reactivity with rm4-1BB, rmCD27, rmCD30, rmCD40, rmFas, rmGITR, rhHVEM, rhNGF R, rmOPG, rmRANK, rmTNF RI, rmTROY, or rmEDAR is observed.
- Reactivity
- Mouse
- Host
- Hamster
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells.
Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling.
Raphael I, Gomez-Rivera F, Raphael RA, Robinson RR, Nalawade S, Forsthuber TG
JCI insight 2019 Dec 19;4(24)
JCI insight 2019 Dec 19;4(24)
Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling.
Ansa-Addo EA, Zhang Y, Yang Y, Hussey GS, Howley BV, Salem M, Riesenberg B, Sun S, Rockey DC, Karvar S, Howe PH, Liu B, Li Z
The Journal of clinical investigation 2017 Apr 3;127(4):1321-1337
The Journal of clinical investigation 2017 Apr 3;127(4):1321-1337
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of TNF RII/TNFRSF1B in L-929 Mouse Cell Line by Flow Cytometry. L-929 mouse fibroblast cell line was stained with Hamster Anti-Mouse TNF RII/TNFRSF1B APC-conjugated Monoclonal Antibody (Catalog # FAB426A, filled histogram) or Hamster IgG Allophycocyanin Control Antibody (open histogram). View our protocol for Staining Membrane-associated Proteins.
