TNFRSF1B

gene product
CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
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365 antibodies from 27 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
10 antibodies
antibodies-online
108 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
Novus Biologicals
25 antibodies
Abnova Corporation
7 antibodies
GeneTex
9 antibodies
Thermo Fisher Scientific Pierce
10 antibodies
Acris Antibodies GmbH
35 antibodies
Aviva Systems Biology
5 antibodies
Boster Immunoleader Biotechnology
2 antibodies
LifeSpan BioSciences, Inc.
51 antibodies
RabMAbs
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Creative Biomart
68 antibodies
Enzo Life Sciences
2 antibodies
Biorbyt
2 antibodies
BioLegend (formerly Covance Antibody Products)
1 antibody
Everest Biotech
1 antibody
BioLegend
6 antibodies
GenWay
11 antibodies
RayBiotech, Inc.
2 antibodies
Abiocode, Inc.
1 antibody
Bioworld Technology, Inc
1 antibody
Abbiotec
1 antibody
Sigma-Aldrich
1 antibody
United States Biological
1 antibody