358410
antibody from BioLegend
Targeting: TNFRSF1B
CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 358410 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#358410, RRID:AB_2564394
- Product name
- Biotin anti-human CD120b
- Antibody type
- Monoclonal
- Antigen
- Partial CD120b recombinant protein expressed in 293E cells (22-211aa).
- Description
- CD120b, also known as TNFRII or TNFRSF1B, belongs to the TNF receptor superfamily and can interact with ligands TNF-α and TNF-β (also known as LT-α). It is a 75 kD type I transmembrane protein expressed on lymphocytes, monocytes, and granulocytes. When present in a heterocomplex with CD120a, it induces the recruitment of anti-apoptotic molecules, c-IAP1 and c-IAP2 that possess E3 ubiquitin ligase activity. Mutations in CD120b are associated with TNF-associated periodic syndrome (TRAPS) or periodic fever syndrome.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Biotin
- Antibody clone number
- 3G7A02
- Vial size
- 500 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with biotinylated CD120b (clone 3G7A02) (filled histogram) or biotinylated rat IgG2a, κ isotype control (open histogram), followed by SAV-PE.
- Conjugate
- Biotin