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LearnMAB226
antibody from R&D Systems
Targeting: TNFRSF1B
CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
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- Product number
- MAB226 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human TNF RII/TNFRSF1B Monoclonal Antibody (Clone 22221)
- Antibody type
- Monoclonal
- Antigen
- E. coli-derived recombinant human TNF RII, Leu23-Asp257 (predicted)
- Description
- Protein A or G purified from ascites
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P20333- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes.
Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy.
Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells.
Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators.
Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators.
Stent implantation in coronary porcine arteries is associated with early activation of TNFalpha and TNFalpha receptor II expression.
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
Monguió-Tortajada M, Franquesa M, Sarrias MR, Borràs FE
Cell death & disease 2018 May 1;9(5):499
Cell death & disease 2018 May 1;9(5):499
Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy.
Sonoda Y, Gohda T, Suzuki Y, Omote K, Ishizaka M, Matsuoka J, Tomino Y
PloS one 2015;10(4):e0122212
PloS one 2015;10(4):e0122212
Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
Nomura T, Aoyama M, Waguri-Nagaya Y, Goto Y, Suzuki M, Miyazawa K, Asai K, Goto S
Experimental cell research 2014 Feb 15;321(2):167-77
Experimental cell research 2014 Feb 15;321(2):167-77
FOXO3a regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells.
Ding B, Kirkiles-Smith NC, Pober JS
The Journal of biological chemistry 2009 Jul 17;284(29):19331-9
The Journal of biological chemistry 2009 Jul 17;284(29):19331-9
Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators.
van Mierlo GJ, Scherer HU, Hameetman M, Morgan ME, Flierman R, Huizinga TW, Toes RE
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):2747-51
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):2747-51
Cutting edge: TNFR-shedding by CD4+CD25+ regulatory T cells inhibits the induction of inflammatory mediators.
van Mierlo GJ, Scherer HU, Hameetman M, Morgan ME, Flierman R, Huizinga TW, Toes RE
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):2747-51
Journal of immunology (Baltimore, Md. : 1950) 2008 Mar 1;180(5):2747-51
Stent implantation in coronary porcine arteries is associated with early activation of TNFalpha and TNFalpha receptor II expression.
Hadjadj S, Cloutier I, Geoffroy P, Tanguay JF
Atherosclerosis 2007 May;192(1):25-32
Atherosclerosis 2007 May;192(1):25-32
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Ebert EC, Mehta V
Cellular immunology 2006 May;241(1):7-13
Cellular immunology 2006 May;241(1):7-13
Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
Chopin V, Slomianny C, Hondermarck H, Le Bourhis X
Experimental cell research 2004 Aug 15;298(2):560-73
Experimental cell research 2004 Aug 15;298(2):560-73
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