Tissue expression
Cell line expression
Protein structure
USP8
Ubiquitin specific peptidase 8HumORF8, KIAA0055, SPG59, UBPY
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Top validated antibodies |
|||||
GeneTex | GTX103747 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
Invitrogen Antibodies | PA5-27947 | 1 references | Polyclonal |
WB
ICC
IP
IHC |
|
antibodies-online | ABIN787063 | Polyclonal |
WB
ICC
IP
IHC |
||
Proteintech Group | 27791-1-AP | 4 references | Polyclonal |
WB
EL
IHC
|
|
Novus Biologicals | NBP2-20792 | Polyclonal |
WB
ICC
IP
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider