DMAB8498MR

antibody from Creative Diagnostics

Targeting: ITGB2 CD18, LFA-1, MAC-1, MFI7

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

DMAB8498MR

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DMAB8498MR, RRID:AB_2392274

Product name

Anti-ITGB2 monoclonal antibody, clone PY43

Antibody type

Monoclonal

Description

Mouse anti Rat CD11b, recognizes rat CD11b, also known as integrin alpha-M, the receptor for the iC3b component of complement. CD11b is a 1151 amino acid single pass type 1 transmembrane glycoprotein posessing a single VWFA domain and multiple FG-GAP repeats. CD11b is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglia in the brain (Robinson et al.1986).

Reactivity

Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG