Tissue expression
Cell line expression
Protein structure
ITGB2
Integrin subunit beta 2CD18, LFA-1, MAC-1, MFI7
This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Top validated antibodies |
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Proteintech Group | ![]() |
29 references | Polyclonal |
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GeneTex | ![]() |
2 references | Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
3 references | Monoclonal |
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OriGene | ![]() |
Monoclonal |
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