BS8022

antibody from Bioworld Technology, Inc

Targeting: CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8022

Provider

Bioworld Technology, Inc

Product name

CX3CL1 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human CX3CL1.

Description

Chemokines are members of a superfamily of inducible,secreted, proinflammatorycytokines. Members of the chemokine family exhibit 20-50% homologyin their predicted amino acid sequences and are divided into 4 subfamilies. In the subfamily designated C-C or ÉÇ, the first two cysteines are adjacent. In the C-X-C or Ï« subfamily, the first two of fourcysteine residues are separated by a single amino acid. C subfamilymembers, also designated ÎÛ chemokines, lackthe first and third cysteine residues of the conserved motif. Chemokinesin these three subfamilies are small,secreted proteins. Fractalkine, also designated neurotactin, isthe firstcharacterizedmember of a fourth chemokine subfamily.Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated bythree amino acid residues.Fractalkine mRNA has been detected in brain and heart and is upregulated inmicroglia and endothelialcells byinflammatorysignals. The protein can exist both as a membrane-bound formand as a chemotacticsoluble form.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.