BS60619

antibody from Bioworld Technology, Inc
Targeting: CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1
Provider product page for BS60619

Antibody data

Product number
BS60619 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CX3CL1 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human CX3CL1
Description
Chemokines are members of a superfamily of inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20-50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the subfamily designated C-C or ÉÇ, the first two cysteines are adjacent. In the C-X-C or a subfamily, the first two of four cysteine residues are separated by a single amino acid. C subfamily members, also designated ÎÛ chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins with molecular weights ranging from 7-15 kDa. Fractalkine, also designated neurotactin, is the first characterized member of a fourth chemokine subfamily. Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues. Fractalkine mRNA has been detected in brain and heart and is upregulated in microglia and endothelial cells by inflammatory signals. The protein can exist both as a membranebound form and as a chemotactic soluble form.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CX3CL1 protein structure - BS60619 shown in red.