BS60619
antibody from Bioworld Technology, Inc
Targeting: CX3CL1
ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60619 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CX3CL1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human CX3CL1
- Description
- Chemokines are members of a superfamily of inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20-50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the subfamily designated C-C or ÉÇ, the first two cysteines are adjacent. In the C-X-C or a subfamily, the first two of four cysteine residues are separated by a single amino acid. C subfamily members, also designated ÎÛ chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins with molecular weights ranging from 7-15 kDa. Fractalkine, also designated neurotactin, is the first characterized member of a fourth chemokine subfamily. Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues. Fractalkine mRNA has been detected in brain and heart and is upregulated in microglia and endothelial cells by inflammatory signals. The protein can exist both as a membranebound form and as a chemotactic soluble form.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of CX3CL1 pAb at 1:500 dilutionLane1:MCF-7 whole cell lysateLane2:NIH-3T3 whole cell lysate Lane3:PC12 whole cell lysate