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- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
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- Product number
- 21200-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21200-1-AP, RRID:AB_10733345
- Product name
- PDE6A antibody
- Antibody type
- Polyclonal
- Description
- PDE6A antibody (Cat. #21200-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Mouse models of human ocular disease for translational research.
Ocular toxicity of AUY922 in pigmented and albino rats.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
Luteinizing hormone signaling phosphorylates and activates the cyclic GMP phosphodiesterase PDE5 in mouse ovarian follicles, contributing an additional component to the hormonally induced decrease in cyclic GMP that reinitiates meiosis.
Egbert JR, Yee SP, Jaffe LA
Developmental biology 2018 Mar 1;435(1):6-14
Developmental biology 2018 Mar 1;435(1):6-14
Mouse models of human ocular disease for translational research.
Krebs MP, Collin GB, Hicks WL, Yu M, Charette JR, Shi LY, Wang J, Naggert JK, Peachey NS, Nishina PM
PloS one 2017;12(8):e0183837
PloS one 2017;12(8):e0183837
Ocular toxicity of AUY922 in pigmented and albino rats.
Roman D, VerHoeve J, Schadt H, Vicart A, Walker UJ, Turner O, Richardson TA, Wolford ST, Miller PE, Zhou W, Lu H, Akimov M, Kluwe W
Toxicology and applied pharmacology 2016 Oct 15;309:55-62
Toxicology and applied pharmacology 2016 Oct 15;309:55-62
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.
Datta P, Allamargot C, Hudson JS, Andersen EK, Bhattarai S, Drack AV, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Aug 11;112(32):E4400-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PDE6A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PDE6A. This antibody recognizes human, mouse, rat antigen. The PDE6A antibody has been validated for the following applications: ELISA, WB analysis.
