CABT-BL2869

antibody from Creative Diagnostics

Targeting: PDE6A PDEA, RP43

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-BL2869

Provider

Creative Diagnostics

Product name

Anti-PDE6A polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.