FNab04867

antibody from FineTest Biotech
Targeting: LRWD1 CENP-33, DKFZp434K1815, ORCA
Provider product page for FNab04867
Western blot
ELISA

Antibody data

Product number
FNab04867 - Provider product page
Provider
FineTest Biotech
Product name
LRWD1 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
leucine-rich repeats and WD repeat
domain containing 1
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
LRWD1 protein structure - FNab04867 shown in red.