KCNC2

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Description

Potassium voltage-gated channel subfamily C member 2

Tissue specificity

Tissue enriched (brain)

Predicted location

Membrane

Protein family

Disease related genes
FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)
Voltage-gated ion channels

Chromosome

12 (75040077 - 75209839)

Ensembl ID

ENSG00000166006  (ver. 103.38)

Orthologs

Mouse Kcnc2: ENSMUSG00000035681

UniProt

Q96PR1

neXtProt

NX_Q96PR1

Human splice variants
Mouse splice variants

Protein structure