Tissue expression
Cell line expression
Protein structure
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunitEM9, MAG, MGC102762, MGC126218, MGC126219, XPD
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Top validated antibodies |
|||||
Proteintech Group | 10818-1-AP | 9 references | Polyclonal |
WB
EL
IP
IHC |
|
Invitrogen Antibodies | 10818-1-AP | Polyclonal |
WB
IP
IHC
OA |
||
Novus Biologicals | 25850002 | 2 references | Polyclonal |
WB
EL
IHC
|
|
LSBio | LS-C375659 | Polyclonal |
WB
EL
IHC
|
||
NovoPro Bioscience Inc. | 110408 | Polyclonal |
WB
EL
IP
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider