634702

antibody from BioLegend

Targeting: MMP1 CLG

Western blot (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

634702

Provider

BioLegend

Proper citation

BioLegend Cat#634702, RRID:AB_2144281

Product name

Purified anti-MMP1

Antibody type

Monoclonal

Antigen

Ovalbumin-conjugated synthetic peptide CSSFGFPRTVKH

Description

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X.MMP1 is thought to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction. Clone F15P3B6 has been shown to be useful for western blotting and immunohistochemistry of human MMP1.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4 °C.