Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP1-37775 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-37775, RRID:AB_2158245
- Product name
- Goat Polyclonal P2X7/P2RX7 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Goat
- Antigen sequence
N-Terminus
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references New role of P2X7 receptor in an Alzheimer's disease mouse model.
The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.
Martin E, Amar M, Dalle C, Youssef I, Boucher C, Le Duigou C, Brückner M, Prigent A, Sazdovitch V, Halle A, Kanellopoulos JM, Fontaine B, Delatour B, Delarasse C
Molecular psychiatry 2019 Jan;24(1):108-125
Molecular psychiatry 2019 Jan;24(1):108-125
The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner.
Tomasinsig L, Pizzirani C, Skerlavaj B, Pellegatti P, Gulinelli S, Tossi A, Di Virgilio F, Zanetti M
The Journal of biological chemistry 2008 Nov 7;283(45):30471-81
The Journal of biological chemistry 2008 Nov 7;283(45):30471-81
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: P2X7/P2RX7 Antibody [NBP1-37775] - (0.3ug/ml) of Human Brain (Frontal Cortex) lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-37775] - (3.8ug/ml) staining of Human Brain Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP1-37775] - Staining of Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.