Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB3617 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB3617, RRID:AB_10552680
- Product name
- HRAS monoclonal antibody, clone H-RAS-03
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of HRAS.
- Antigen sequence
DIHQYREQIKRVKDSDDC
- Isotype
- IgG
- Antibody clone number
- H-RAS-03
- Storage
- Store at 4°C. Do not freeze.Aliquot to avoid repeated freezing and thawing.
Submitted references The Hsp90 molecular chaperone: an open and shut case for treatment.
Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol.
Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis.
Pearl LH, Prodromou C, Workman P
The Biochemical journal 2008 Mar 15;410(3):439-53
The Biochemical journal 2008 Mar 15;410(3):439-53
Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol.
Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW
The FEBS journal 2007 Sep;274(17):4453-63
The FEBS journal 2007 Sep;274(17):4453-63
Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis.
Hooven TA, Yamamoto Y, Jeffery WR
The International journal of developmental biology 2004;48(8-9):731-8
The International journal of developmental biology 2004;48(8-9):731-8
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western Blotting analysis (reducing conditions) of HRAS in whole cell lysate using HRAS monoclonal antibody, clone H-RAS-03 (Cat # MAB3617).Lane 1 : HeLa, human cervix carcinoma cell line.Lane 2 : K-567, human leukemia cell line.Lane 3 : RAJI, human Burkitt lymphoma cell line.