HRAS

gene product
HRAS1
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
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184 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
5 antibodies
Novus Biologicals
10 antibodies
antibodies-online
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Proteintech Group
1 antibody
Aviva Systems Biology
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GeneTex
6 antibodies
Abgent
3 antibodies
Abnova Corporation
6 antibodies
Signalway Antibody LLC
1 antibody
LifeSpan BioSciences, Inc.
24 antibodies
Acris Antibodies GmbH
6 antibodies
Creative Biomart
23 antibodies
RabMAbs
3 antibodies
Biorbyt
23 antibodies
Abbiotec
1 antibody
Bioworld Technology, Inc
1 antibody
United States Biological
11 antibodies
EMD Millipore
3 antibodies
Sigma-Aldrich
2 antibodies
Sino Biological Inc.
1 antibody