AUP1

gene product
This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25. [provided by RefSeq, Jul 2008]
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Supportive data in Antibodypedia
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Validated in Knockdown Initative
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88 antibodies from 17 providers.

Antibody properties

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
3 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Bethyl Laboratories, Inc.
3 antibodies
antibodies-online
31 antibodies
Abnova Corporation
2 antibodies
OriGene
3 antibodies
LifeSpan BioSciences, Inc.
12 antibodies
Sigma-Aldrich
1 antibody
Aviva Systems Biology
2 antibodies
Acris Antibodies GmbH
1 antibody
Biorbyt
2 antibodies
Cell Signaling Technology, Inc
1 antibody
United States Biological
9 antibodies
Thermo Fisher Scientific Pierce
1 antibody
Creative Diagnostics
3 antibodies