AUP1

gene product
The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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125 antibodies from 20 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Proteintech Group
1 antibody
antibodies-online
40 antibodies
Novus Biologicals
3 antibodies
Atlas Antibodies
1 antibody
Bethyl Laboratories, Inc.
3 antibodies
Abnova Corporation
2 antibodies
LifeSpan BioSciences, Inc.
16 antibodies
OriGene
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Sigma-Aldrich
1 antibody
Aviva Systems Biology
2 antibodies
Biorbyt
3 antibodies
Acris Antibodies GmbH
1 antibody
United States Biological
26 antibodies
MyBioSource
3 antibodies
St John's Laboratory
1 antibody
Creative Diagnostics
3 antibodies
Abgent
1 antibody
Invitrogen Antibodies
1 antibody