Explore
Validate
LearnABIN500467
antibody from antibodies-online
Targeting: CD274
B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN500467 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-CD274 Molecule (CD274) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- PDL-1 antibody was raised against a 17 amino acid peptide from near the center of human PDL-1.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanism.
Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1).
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Chentoufi AA, Kritzer E, Tran MV, Dasgupta G, Lim CH, Yu DC, Afifi RE, Jiang X, Carpenter D, Osorio N, Hsiang C, Nesburn AB, Wechsler SL, BenMohamed L
Journal of virology 2011 Sep;85(17):9127-38
Journal of virology 2011 Sep;85(17):9127-38
Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1).
LaGier AJ, Pober JS
Human immunology 2006 Aug;67(8):568-78
Human immunology 2006 Aug;67(8):568-78
Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.
Holling TM, Schooten E, van Den Elsen PJ
Human immunology 2004 Apr;65(4):282-90
Human immunology 2004 Apr;65(4):282-90
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
Ishida Y, Agata Y, Shibahara K, Honjo T
The EMBO journal 1992 Nov;11(11):3887-95
The EMBO journal 1992 Nov;11(11):3887-95
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of PDL-1 in Raji cell lysate with AP30655PU-N at (A) 0.5 and (B) 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunofluorescence of PDL-1 in Human Heart cells with PDL-1 antibody AP30655PU-N at 20 ug/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of PDL-1 in human heart tissue with AP30655PU-N at 2.5 ?g/ml.
