Tissue expression
Cell line expression
Protein structure
CD70
CD70 moleculeCD27L, CD27LG, TNFSF7
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
3 references | Monoclonal |
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Antibodies.com | ![]() |
Monoclonal |
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NSJ Bioreagents | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
6 references | Monoclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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