BS8702

antibody from Bioworld Technology, Inc

Targeting: UPF2 DKFZP434D222, KIAA1408, RENT2, smg-3

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS8702

Provider

Bioworld Technology, Inc

Product name

UPF2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Regulator of nonsense transcripts 2; Nonsense mRNA reducing factor 2; Up-frameshift suppressor 2 homolog; hUpf2; UPF2; KIAA1408, RENT2

Description

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.