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Protein structure
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5CEB1
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00051191-A01 |
5 references | Polyclonal |
WB
EL
ICC
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| Proteintech Group | 22692-1-AP |
4 references | Polyclonal |
EL
IP
IHC
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| Invitrogen Antibodies | 22692-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Enzo Life Sciences | BML-PW0920-0025 |
1 references | Polyclonal |
WB
ICC
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| NSJ Bioreagents | RQ5045 |
Polyclonal |
WB
EL
ICC
|
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