Tissue expression
Cell line expression
Protein structure
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5CEB1
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | H00051191-A01 | 5 references | Polyclonal |
WB
EL
ICC
|
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Proteintech Group | 22692-1-AP | 2 references | Polyclonal |
EL
IP
IHC
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Invitrogen Antibodies | 22692-1-AP | Polyclonal |
WB
IP
IHC
OA |
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Enzo Life Sciences | BML-PW0920-0025 | 1 references | Polyclonal |
WB
ICC |
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Boster Biological Technology | A05285-2 | Polyclonal |
WB
EL
ICC
|
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Supportive data in Antibodypedia
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Recommended by provider