BS3029

antibody from Bioworld Technology, Inc
Targeting: GRID2 GluD2, GluR-delta-2
Provider product page for BS3029
Western blot
Immunocytochemistry

Antibody data

Product number
BS3029 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3029, RRID:AB_1662568
Product name
GluR Ñ´2 (G860) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 831-880 of Human GluR-Ñ´2.
Description
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR-Ñ´2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: š÷1, 2, 3, 4 and one šø subunit. The šø subunit is expressed throughout the brainstem whereas the four š÷ subunits display limited distribution. In mice, mutations in the gene encoding GluR-Ñ´2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR-Ñ´2 maps to chromosome 4q22.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GRID2 protein structure - BS3029 shown in red.