Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN500827 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Stromal Interaction Molecule 1 (STIM1) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- STIM1 antibody was raised against a 24 amino acid peptide from near the carboxy terminus of human STIM1.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1,0 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells.
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels.
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Luik RM, Lewis RS
Trends in molecular medicine 2007 Mar;13(3):103-7
Trends in molecular medicine 2007 Mar;13(3):103-7
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function.
Feske S, Gwack Y, Prakriya M, Srikanth S, Puppel SH, Tanasa B, Hogan PG, Lewis RS, Daly M, Rao A
Nature 2006 May 11;441(7090):179-85
Nature 2006 May 11;441(7090):179-85
STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels.
Spassova MA, Soboloff J, He LP, Xu W, Dziadek MA, Gill DL
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 14;103(11):4040-5
Proceedings of the National Academy of Sciences of the United States of America 2006 Mar 14;103(11):4040-5
STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.
Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH, Stauderman KA, Cahalan MD
Nature 2005 Oct 6;437(7060):902-5
Nature 2005 Oct 6;437(7060):902-5
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of STIM1 in mouse thymus tissue lysate with AP30837PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of STIM1 in human spleen tissue with AP30837PU-N at 2.5 ?g/ml.