STIM1

gene product
D11S4896E, GOK
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
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227 antibodies from 28 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
31 antibodies
Abnova Corporation
6 antibodies
Proteintech Group
2 antibodies
antibodies-online
69 antibodies
Acris Antibodies GmbH
11 antibodies
Cell Signaling Technology, Inc
3 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
34 antibodies
Thermo Fisher Scientific Pierce
5 antibodies
GeneTex
4 antibodies
Aviva Systems Biology
2 antibodies
Biorbyt
1 antibody
Bethyl Laboratories, Inc.
2 antibodies
ProSci
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
Everest Biotech
1 antibody
RabMAbs
2 antibodies
Creative Biomart
14 antibodies
R&D Systems
2 antibodies
RayBiotech, Inc.
4 antibodies
Sino Biological Inc.
2 antibodies
Enzo Life Sciences
1 antibody
United States Biological
18 antibodies
Sigma-Aldrich
5 antibodies
Abbiotec
1 antibody
Abgent
1 antibody
EMD Millipore
1 antibody
GenWay
1 antibody