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LearnTissue expression
Cell line expression
Protein structure
LAT
Linker for activation of T cellsLAT1
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11326-1-AP |
2 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN393665 |
5 references | Monoclonal |
WB
EL
IHC
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| Atlas Antibodies | HPA011157 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | 11326-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| Cusabio Biotech Co., Ltd | CSB-RA012767A191phHU |
Recombinant |
WB
EL
ICC
IP
IHC
|
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