ABIN360502

antibody from antibodies-online

Targeting: EIF2AK3 PEK, PERK

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN360502

Provider

antibodies-online

Product name

anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 3 (EIF2AK3) (N-Term) antibody

Antibody type

Polyclonal

Description

Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Pancreatic eukaryotic initiation factor-2alpha kinase (PEK) homologues in humans, Drosophila melanogaster and Caenorhabditis elegans that mediate translational control in response to endoplasmic reticulum stress.

Sood R, Porter AC, Ma K, Quilliam LA, Wek RC
The Biochemical journal 2000 Mar 1;346 Pt 2:281-93

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EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome.

Delépine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C
Nature genetics 2000 Aug;25(4):406-9

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Characterization of a mutant pancreatic eIF-2alpha kinase, PEK, and co-localization with somatostatin in islet delta cells.

Shi Y, An J, Liang J, Hayes SE, Sandusky GE, Stramm LE, Yang NN
The Journal of biological chemistry 1999 Feb 26;274(9):5723-30