Tissue expression
Cell line expression
Protein structure
ABCE1
ATP binding cassette subfamily E member 1OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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GeneTex | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
4 references | Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Recombinant |
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