ISYNA1

This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

Description

Inositol-3-phosphate synthase 1

Tissue specificity

Tissue enhanced (choroid plexus, testis)

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

19 (18434388 - 18438167)

Ensembl ID

ENSG00000105655  (ver. 103.38)

Orthologs

Mouse Isyna1: ENSMUSG00000019139

UniProt

Q9NPH2

neXtProt

NX_Q9NPH2

Human splice variants
Mouse splice variants

Protein structure