PAB13357

antibody from Abnova Corporation

Targeting: IRGM IFI1, IRGM1, LRG-47, LRG47

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB13357

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB13357, RRID:AB_10555326

Product name

IRGM polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of IRGM.

Storage

Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.

Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L, Wellcome Trust Case Control Consortium, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J
Nature genetics 2008 Jun;40(6):710-2

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Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease.

Massey DC, Parkes M
Autophagy 2007 Nov-Dec;3(6):649-51

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Autophagy as a cell death and tumor suppressor mechanism.

Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of IRGM in rat brain tissue lysate with IRGM polyclonal antibody (Cat # PAB13357) at (A) 1 and (B) 2 ug/mL .