Tissue expression
Cell line expression
Protein structure
IRGM
Immunity related GTPase MIFI1, IRGM1, LRG-47, LRG47
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
Top validated antibodies |
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GeneTex | GTX85038 | Polyclonal |
WB
EL
ICC
IHC |
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LSBio | LS-C53283 | Polyclonal |
WB
EL
ICC
IHC |
||
antibodies-online | ABIN500070 | 4 references | Polyclonal |
WB
IHC |
|
Novus Biologicals | NBP1-76377 | Polyclonal |
WB
EL
ICC
IHC |
||
Boster Biological Technology | A03614 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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