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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB13358 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13358, RRID:AB_10555325
- Product name
- IRGM polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of IRGM.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease.
Autophagy as a cell death and tumor suppressor mechanism.
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L, Wellcome Trust Case Control Consortium, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J
Nature genetics 2008 Jun;40(6):710-2
Nature genetics 2008 Jun;40(6):710-2
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease.
Massey DC, Parkes M
Autophagy 2007 Nov-Dec;3(6):649-51
Autophagy 2007 Nov-Dec;3(6):649-51
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of IRGM in human brain tissue lysate with IRGM polyclonal antibody (Cat # PAB13358) at (A) 1 and (B) 2 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of IRGM in human brain with IRGM polyclonal antibody (Cat # PAB13358) at 5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
