Tissue expression
Cell line expression
Protein structure
NACA
Nascent polypeptide associated complex subunit alphaNACA1
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016]
Top validated antibodies |
|||||
Invitrogen Antibodies | 40-1000 | 1 references | Polyclonal |
WB
OA |
|
Novus Biologicals | H00004666-B01P | 1 references | Polyclonal |
WB
ICC |
|
Abnova Corporation | H00004666-B01P | 1 references | Polyclonal |
WB
ICC |
|
antibodies-online | ABIN518179 | 1 references | Polyclonal |
WB
ICC |
|
Boster Biological Technology | A02155 | Polyclonal |
WB
IP
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider