BS7459

antibody from Bioworld Technology, Inc
Targeting: GRM1 GPRC1A, mGlu1, MGLUR1, PPP1R85
Provider product page for BS7459
Western blot
Immunohistochemistry

Antibody data

Product number
BS7459 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GRM1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GRM1.
Description
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GRM1 protein structure - BS7459 shown in red.