Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
FYCO1
FYVE and coiled-coil domain autophagy adaptor 1FLJ13335, ZFYVE7
The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020]
Top validated antibodies |
|||||
| LSBio |  LS-C379409 |
Polyclonal |
WB
EL
IHC
|
||
| Atlas Antibodies | HPA035526 |
6 references | Polyclonal |
ICC
IHC
|
|
| Novus Biologicals | NBP1-47266 |
2 references | Polyclonal |
WB
IP
|
|
| Biorbyt | orb1420531 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Invitrogen Antibodies | PA5-119696 |
Polyclonal |
WB
IHC
FC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider