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LearnABIN1881802
antibody from antibodies-online
Targeting: SH2D1A
DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN1881802 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SH2 Domain Containing 1A (SH2D1A) (C-Term), (AA 85-114) antibody
- Antibody type
- Polyclonal
- Antigen
- This SH2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the C-terminal region of human SH2D1A.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 85-114
- Antibody clone number
- RB41923
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency.
The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease.
SLAM receptors and SAP influence lymphocyte interactions, development and function.
SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux.
Snow AL, Marsh RA, Krummey SM, Roehrs P, Young LR, Zhang K, van Hoff J, Dhar D, Nichols KE, Filipovich AH, Su HC, Bleesing JJ, Lenardo MJ
The Journal of clinical investigation 2009 Oct;119(10):2976-89
The Journal of clinical investigation 2009 Oct;119(10):2976-89
The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease.
Nagy N, Matskova L, Kis LL, Hellman U, Klein G, Klein E
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 21;106(29):11966-71
Proceedings of the National Academy of Sciences of the United States of America 2009 Jul 21;106(29):11966-71
SLAM receptors and SAP influence lymphocyte interactions, development and function.
Schwartzberg PL, Mueller KL, Qi H, Cannons JL
Nature reviews. Immunology 2009 Jan;9(1):39-46
Nature reviews. Immunology 2009 Jan;9(1):39-46
SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux.
Ostrakhovitch EA, Wang Y, Li SS
Cellular signalling 2009 Apr;21(4):540-50
Cellular signalling 2009 Apr;21(4):540-50
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- SH2D1A Antibody (C-term) (ABIN1881802) western blot analysis in 293 cell line lysates (35 μg/lane). This demonstrates the SH2D1A antibody detected the SH2D1A protein (arrow).
