abx117040

antibody from Abbexa

Targeting: SH2D1A DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx117040

Provider

Abbexa

Product name

SH2 Domain Containing 1A (SH2D1A) Antibody

Antibody type

Polyclonal

Description

SH2D1A Antibody is a Rabbit Polyclonal antibody against SH2D1A. SH2D1A and SH2D1B are small, adaptor proteins with a single SH2-domain that play important signal transduction roles mediated by the signaling lymphocytic activation molecule (SLAM) family receptorsSH2D1A (also called SAP or SLAM-associated protein) is frequently mutated in patients with X-linked lymphoprolifeRative disease (Duncan’s disease), which is characterized by extreme susceptibility to Epstein-Barr virus; approximately 50 different SH2D1A mutations have been reported to dateThe single SH2D1B gene in humans (also called EAT-2 or Ewings sarcomas/FLI1-activated transcript 2) is present as a pair of duplicated EAT-2A and EAT-2B genes with identical genomic organization in mouse and Rat.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µg

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.