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PON2
Paraoxonase 2This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  14379-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 14379-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| NovoPro Bioscience Inc. | 114059 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| antibodies-online | ABIN954246 |
4 references | Polyclonal |
WB
IHC
FC
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| Novus Biologicals | NBP1-52005 |
1 references | Polyclonal |
WB
EL
IHC
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