PC

gene product
PCB
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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134 antibodies from 22 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
12 antibodies
Proteintech Group
1 antibody
antibodies-online
32 antibodies
Atlas Antibodies
1 antibody
Biorbyt
12 antibodies
GeneTex
7 antibodies
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
3 antibodies
Thermo Fisher Scientific Pierce
2 antibodies
Abnova Corporation
1 antibody
Abgent
2 antibodies
OriGene
6 antibodies
LifeSpan BioSciences, Inc.
18 antibodies
Bioworld Technology, Inc
1 antibody
Everest Biotech
1 antibody
RabMAbs
4 antibodies
EMD Millipore
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
8 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies