PC

gene product
PCB
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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92 antibodies from 15 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
12 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Acris Antibodies GmbH
3 antibodies
LifeSpan BioSciences, Inc.
14 antibodies
GeneTex
4 antibodies
Abnova Corporation
1 antibody
Thermo Fisher Scientific Pierce
1 antibody
antibodies-online
32 antibodies
Everest Biotech
1 antibody
Aviva Systems Biology
4 antibodies
RabMAbs
4 antibodies
United States Biological
7 antibodies
Creative Biomart
5 antibodies
Sigma-Aldrich
2 antibodies