PC

gene product
PCB
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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94 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
13 antibodies
antibodies-online
21 antibodies
Proteintech Group
1 antibody
Atlas Antibodies
1 antibody
Acris Antibodies GmbH
3 antibodies
Aviva Systems Biology
4 antibodies
Biorbyt
5 antibodies
GeneTex
4 antibodies
Abnova Corporation
1 antibody
Abgent
1 antibody
LifeSpan BioSciences, Inc.
15 antibodies
Thermo Fisher Scientific Pierce
1 antibody
Everest Biotech
1 antibody
RabMAbs
4 antibodies
EMD Millipore
2 antibodies
Bioworld Technology, Inc
1 antibody
RayBiotech, Inc.
1 antibody
United States Biological
8 antibodies
Creative Biomart
5 antibodies
Sigma-Aldrich
2 antibodies