PC

gene product
PCB
This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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197 antibodies from 27 providers.

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AntibodyRefsTypeKDWBELICCIPIHCFC
Novus Biologicals
12 antibodies
antibodies-online
35 antibodies
GeneTex
6 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
LifeSpan BioSciences, Inc.
34 antibodies
Biorbyt
13 antibodies
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
3 antibodies
Abnova Corporation
1 antibody
OriGene
6 antibodies
Arigo
2 antibodies
Abgent
3 antibodies
Bioworld Technology, Inc
1 antibody
Everest Biotech
1 antibody
Creative Biolabs
3 antibodies
RabMAbs
4 antibodies
NSJ Bioreagents
1 antibody
MyBioSource
6 antibodies
St John's Laboratory
2 antibodies
EMD Millipore
2 antibodies
Invitrogen Antibodies
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
37 antibodies
Creative Diagnostics
2 antibodies
Sigma-Aldrich
2 antibodies