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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS4787 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS4787, RRID:AB_1663144
- Product name
- eIF2Ï« (phospho S51) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic phosphopeptide derived from human eIF2Ï« around the phosphorylation site of Serine 51.
- Description
- eIF2Ï«, also known as EIF2S1 or EIF2, is a 315 amino acid subunit of the eukaryotic initiation complex that functions to bind tRNA to the 40S ribosomal subunit (in a GTP-dependent manner), thereby initiating translation. In addition, the phosphorylation state of eIF2Ï« controls the rate of tRNA translation. When eIF2Ï« is not phosphorylated, translation occurs at a normal rate. However, upon phosphorylation by one of several kinases, eIF2Ï« is stabilized, thus preventing the GDP/GTP exchange reaction and slowing translation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of p-eIF2¦Á (S51) pAb at 1:500 dilutionLane1:HepG2 whole cell lysateLane2:H9C2 whole cell lysate
