SNRNP200

gene product
ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]
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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
3 antibodies
Abnova Corporation
1 antibody
Atlas Antibodies
1 antibody
Bethyl Laboratories, Inc.
2 antibodies
Proteintech Group
1 antibody
antibodies-online
2 antibodies
Aviva Systems Biology
1 antibody
LifeSpan BioSciences, Inc.
4 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
1 antibody