abx004666

antibody from Abbexa

Targeting: SNRNP200 ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD

Western blot (Recommended by provider)

Antibody Data

Product number

abx004666

Provider

Abbexa

Product name

Small Nuclear Ribonucleoprotein U5 Subunit 200 (SNRNP200) Antibody

Antibody type

Monoclonal

Description

SNRNP200 Antibody is a Rabbit Monoclonal antibody against SNRNP200. Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.