Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
UBE4A
Ubiquitination factor E4AE4, KIAA0126, UBOX2, UFD2
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  MA5-44916 |
Monoclonal |
WB
ICC
IHC
FC
|
||
| Proteintech Group | 21548-1-AP |
1 references | Polyclonal |
WB
EL
IP
|
|
| Novus Biologicals | H00009354-M08 |
Monoclonal |
WB
EL
ICC
|
||
| Abnova Corporation | H00009354-M08 |
Monoclonal |
WB
EL
ICC
|
||
| antibodies-online | ABIN393537 |
Monoclonal |
WB
EL
ICC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider