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UBE4A
Ubiquitination factor E4AE4, KIAA0126, UBOX2, UFD2
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]
Top validated antibodies |
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| Proteintech Group |  21548-1-AP |
2 references | Polyclonal |
WB
EL
IP
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| Invitrogen Antibodies | MA5-44916 |
Monoclonal |
WB
ICC
IHC
FC
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| Novus Biologicals | H00009354-M08 |
Monoclonal |
WB
EL
ICC
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| Abnova Corporation | H00009354-M08 |
Monoclonal |
WB
EL
ICC
|
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| LSBio | LS-C160390 |
Polyclonal |
WB
IHC
|
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