Tissue expression
Cell line expression
Protein structure

MGMT

O-6-methylguanine-DNA methyltransferase
 
Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
More gene data

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973 antibodies from 42 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
79 antibodies
MA3-1653711Monoclonal
MA5-1350666Monoclonal
antibodies-online
240 antibodies
ABIN15120220Monoclonal
ABIN4880865Monoclonal
Novus Biologicals
83 antibodies
NB100-16816Monoclonal
H00004255-M01Monoclonal
Proteintech Group
4 antibodies
17195-1-AP9Polyclonal
67476-1-IgMonoclonal
GeneTex
6 antibodies
GTX270452Monoclonal
GTX231441Monoclonal
OriGene
74 antibodies
TA3249271Polyclonal
UM8000061Monoclonal
Biorbyt
78 antibodies
orb379006Polyclonal
orb1193313Polyclonal
Boster Biological Technology
3 antibodies
PB9266Polyclonal
A01012-1Polyclonal
NSJ Bioreagents
7 antibodies
F50325Polyclonal
F52339Monoclonal
Affinity Biosciences
4 antibodies
AF5295Polyclonal
DF6132Polyclonal
Arigo
3 antibodies
ARG54861Monoclonal
ARG54862Polyclonal
Abnova Corporation
9 antibodies
MAB12338Monoclonal
MAB23833Monoclonal
Abgent
5 antibodies
AP7341bPolyclonal
AP12883aPolyclonal
HUABIO Research
3 antibodies
ER40104Polyclonal
ET1701-55Monoclonal
NovoPro Bioscience Inc.
1 antibody
112603Polyclonal
LS-C357431Polyclonal
LS-C801400Polyclonal
Enzo Life Sciences
3 antibodies
ADI-KAP-TF1213-E1Polyclonal
ADI-KAP-TF121-EPolyclonal
Bioworld Technology, Inc
2 antibodies
BS6049Polyclonal
BS2540Polyclonal
Aviva Systems Biology
2 antibodies
OAAB04338Polyclonal
ARP42038_P050Polyclonal
Bioss
2 antibodies
bs-1002R1Polyclonal
bsm-52742RMonoclonal
Cusabio Biotech Co., Ltd
9 antibodies
CSB-PA003238Polyclonal
CSB-PA013788GA01HUPolyclonal
Cell Signaling Technology, Inc
3 antibodies
58121Monoclonal
86039Monoclonal
Wuhan Fine Biotech Co., Ltd.
2 antibodies
FNab05169Polyclonal
FNab10100Polyclonal
Atlas Antibodies
3 antibodies
HPA032136Polyclonal
HPA069497Polyclonal
R&D Systems
3 antibodies
AF37941Polyclonal
MAB32991Monoclonal
St John's Laboratory
5 antibodies
STJ94115Polyclonal
STJ180172Monoclonal
Acris Antibodies GmbH
7 antibodies
AM00250PU-NMonoclonal
AP20557PU-NPolyclonal
ProSci
1 antibody
62-838Polyclonal
Aladdin Scientific Corporation
1 antibody
Ab115239Polyclonal
United States Biological
77 antibodies
M3884-91Monoclonal
M3884-91-APMonoclonal
Abbexa
21 antibodies
abx016164Monoclonal
abx129084Polyclonal
Abbkine Scientific Co.Ltd.
1 antibody
ABP51789Polyclonal
RabMAbs
4 antibodies
3131-1Monoclonal
3137-1Monoclonal
MyBioSource
6 antibodies
MBS9200128Monoclonal
MBS127905Polyclonal
EMD Millipore
1 antibody
MAB16200Monoclonal
Creative Biolabs
22 antibodies
MOB-2127z-F(E)Monoclonal
MOB-2127z-S(P)Monoclonal
Creative Diagnostics
6 antibodies
DCABH-7580Monoclonal
CABT-L837Monoclonal
Abbiotec
1 antibody
251378Polyclonal
Abiocode, Inc.
1 antibody
R1598-2Polyclonal
Active Motif
1 antibody
39951Polyclonal
MilliporeSigma / Merck KGaA
5 antibodies
HPA069497Polyclonal
WH0004255M1Monoclonal
CPTAC
1 antibody
CPTC-MGMT-1Monoclonal