Tissue expression
Cell line expression
Protein structure
SUMO4
Small ubiquitin like modifier 4dJ281H8.4, IDDM5, SMT3H4
This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ABIN2845831 | 5 references | Polyclonal |
WB
IHC |
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Novus Biologicals | NBP2-67906 | Monoclonal |
WB
ICC
IP
FC |
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Boster Biological Technology | A06740-1 | Polyclonal |
WB
ICC
IP
FC |
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Abnova Corporation | PAB2428 | 3 references | Polyclonal |
WB
IHC |
|
HUABIO Research | ET1701-8 | Monoclonal |
WB
ICC
IP
FC |
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