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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2429 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2429, RRID:AB_1581144
- Product name
- SUMO4 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SUMO4 (M55 Wild type).
- Antigen sequence
CEPRGLS(M)KQIRFRFG- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes.
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.
Park Y, Park S, Kang J, Yang S, Kim D
Nature genetics 2005 Feb;37(2):112; author reply 112-3
Nature genetics 2005 Feb;37(2):112; author reply 112-3
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
Bohren KM, Nadkarni V, Song JH, Gabbay KH, Owerbach D
The Journal of biological chemistry 2004 Jun 25;279(26):27233-8
The Journal of biological chemistry 2004 Jun 25;279(26):27233-8
A functional variant of SUMO4, a new I kappa B alpha modifier, is associated with type 1 diabetes.
Guo D, Li M, Zhang Y, Yang P, Eckenrode S, Hopkins D, Zheng W, Purohit S, Podolsky RH, Muir A, Wang J, Dong Z, Brusko T, Atkinson M, Pozzilli P, Zeidler A, Raffel LJ, Jacob CO, Park Y, Serrano-Rios M, Larrad MT, Zhang Z, Garchon HJ, Bach JF, Rotter JI, She JX, Wang CY
Nature genetics 2004 Aug;36(8):837-41
Nature genetics 2004 Aug;36(8):837-41
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SUMO4 polyclonal antibody (Cat # PAB2429) in HepG2 cell line lysate (35 ug/lane). SUMO4 wild type (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SUMO4 polyclonal antibody (Cat # PAB2429) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
