Tissue expression
Cell line expression
Protein structure
PSMB1
Proteasome 20S subunit beta 1HC5, PMSB1
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA5-49648 | 2 references | Polyclonal |
WB
ICC
IHC
FC
OA
|
|
Proteintech Group | 11749-1-AP | 15 references | Polyclonal |
WB
EL
ICC
IHC |
|
antibodies-online | ABIN2842525 | 1 references | Polyclonal |
WB
ICC
IHC
FC |
|
Abgent | AP8856B | Polyclonal |
WB
ICC
IHC
FC |
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NSJ Bioreagents | F54465 | Polyclonal |
WB
ICC
IHC
FC |
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