Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
TNFAIP6
TNF alpha induced protein 6TSG-6, TSG6
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis. [provided by RefSeq, Dec 2010]
Top validated antibodies |
|||||
| LSBio |  LS-C352947 |
Polyclonal |
WB
IP
IHC
|
||
| Proteintech Group | 13321-1-AP |
6 references | Polyclonal |
WB
EL
|
|
| Cusabio Biotech Co., Ltd | CSB-PA050273 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Novus Biologicals | NBP2-38637 |
1 references | Polyclonal |
WB
IHC
|
|
| Biorbyt | orb674577 |
Polyclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider